Taking OK "Lindinet" during menstruation. Started your period ahead of schedule when taking Lindinet Started your period ahead of schedule with Lindinet 20

01.04.2024

Many young girls use oral contraceptives for protection. It is convenient, reliable, and in addition, it can also treat some pathological conditions. But the body responds to any hormonal drugs in its own way: there are delays, spotting, mood changes, as well as some other signs.

Lindinet 20 and 30 are among the first contraceptive drugs and are still actively used for treatment and for the purpose of preventing pregnancy. How to use the tablets correctly, what are the features of the medicine? What should you do if, while taking Lindinet, you continue to experience previous symptoms during your period?

Read in this article

Admission rules

Lindinet is a combined oral contraceptive that contains estrogen and progestogen components. The package contains 21 tablets for daily use. This is a monophasic drug, which means that each capsule contains the same amount of active ingredients. Lindinet is most suitable for young active girls who are not overweight and have pronounced weight loss.

Standard dosage regimen

Under normal conditions, Lindinet should be taken at the moment when any bleeding from the genital tract appears. At a fixed time, take a tablet daily for 21 days. After this you need to take a break for seven days. At this time, the woman will experience menstrual-like discharge from the genital tract. The first capsule from the next pack must be taken on the 8th day (they will coincide with the day of the week of taking the tablet from the previous pack).

If you start drinking Lindinet after others are OK

In this case, the first pill from the package must be taken as soon as you finish taking other contraceptives. It is possible that spotting will already begin, but there may not be any. The same must be done when removing a contraceptive ring, patch, etc.

If a woman switches to Lindinet-20 or 30 after taking progestin medications (mini-pills), then you can start using these tablets on any day of the cycle.

After termination of pregnancy

In cases where a medical surgical abortion was performed before 12 weeks of pregnancy, you can start taking Lindinet on the same or the next day. There is no need to wait for the next critical days to come. In this case, taking Lindinet, scanty periods in the next cycle are the absolute norm.

If termination of pregnancy occurred after 12 weeks, or after childbirth, Lindinet can be used after a 28-day break. And even if used correctly, it is necessary to take additional measures to protect against unwanted pregnancy during the first seven days.

If the timing of taking pills is incorrect

It happens that a woman forgets to take a pill at the specified time. What matters is what kind of break you get.

If less than 12 hours have passed, you should take the medicine immediately upon detection. The next tablet is as scheduled.

If more than 12 hours have passed, then there is no point in taking the missed pill, you just need to skip it and start with the next one on schedule. But in this case, the risk of pregnancy increases, so it is necessary to use additional methods of contraception for seven days.

If at the time when there was a missed pill, there were 6 - 7 pieces left in the package, then immediately after finishing this pack you need to start a new one without interruption. When taking Lindinet in this mode, your period will be in 50 - 60 days, but the possibility of spotting throughout the entire time cannot be ruled out.

If a woman missed two tablets, then she should proceed as in the previous case. If it’s three, it’s better to throw away the current package, start a new one, or stop taking hormonal medications altogether. In the first week after such a violation of the schedule, it is necessary to use additional methods of birth control.

Watch the video about the use of hormonal contraception:

Impact on the cycle

Lindinet is a combined monophasic contraceptive. This determines its influence on. There are two types of the drug, which differ in the dose of the estrogen component - 0.02 and 0.03 mg. This also affects the likelihood of adverse reactions.

Normal when taking pills

Ideally, regular use of Lindinet should normalize a woman's menstrual cycle to a duration of 28 - 30 days. With the use of the drug, the amount of monthly blood lost decreases.

The main characteristics of menstruation while taking Lindinet with successful administration of the drug:

, sometimes of a smearing nature. If you previously experienced very heavy periods, then using the tablets significantly reduces the volume of menstrual blood.
occur rarely and are short-lived; the use of analgesics is not required.
often 2 - 3 days, less often - 4 - 5. Minor discomfort may occur for up to 7 days.
The cycle is regular, premenstrual symptoms are absent or mild.

The use of Lindinet reduces or virtually eliminates pain on the eve of and during menstruation. This contraceptive drug, by normalizing a woman’s hormonal levels, reduces the likelihood of developing.

In most cases, menstruation after discontinuation of Lindinet acquires previously existing unpleasant symptoms within 3 to 4 cycles.

Lengthening cycle

Sometimes a woman, for some reason, needs to lengthen her menstrual cycle. This can be achieved using Lindinet. But you need to think about this at least 30 - 40 days in advance. To increase the cycle to 50 - 60 days, you should not take a break between two packages. Then in one of the cycles there will simply be no periods; they will come after the end of the second pack. It’s rare, but it still happens that on the days of your expected period, a slight spotting may appear.

Cycle reduction

If you need to shift the beginning or end of the next cycle by several days, you should take a break of not seven, but less than a day (exactly how much you need to change the duration). This, too, can only be done a month in advance.

Unwanted cycle changes

Not everything always goes smoothly while taking birth control pills. It happens that after Lindinet, “menstruation” begins in the middle of the cycle or does not occur at all. Indeed, monophasic drugs have a rather harsh effect on a woman’s body. After all, normally the level of hormones constantly fluctuates, and the tablets contain a strictly fixed dose. Over the course of several months, the body adapts to the new regime, which is sometimes expressed by various types of discharge and symptoms.

The most common violations are the following:

After taking the first pill, your periods stop or become unusually light. This occurs often, as a rule, and in the future menstruation will not be abundant and will not last long.
Spotting, irregular bleeding from the genital tract appears. This can continue for a month or even two. In most cases, nothing should be done; the cycle will establish itself after a while. But sometimes the dose of the hormone in the drug may not be enough, in particular if the girl takes Lindinet-20.

In such a situation, switching to 0.03 mg of estrogen will solve the whole problem. Spotting may be associated with a mismatch between a woman’s biological rhythms and the time of taking pills. To eliminate this factor, you should change the schedule, for example, from morning to evening or vice versa. This often helps the body adapt faster.

The package was drunk, and my period came only on the 5th - 6th day of the break. This is normal. It is allowed that menstruation begins on one of the days, not necessarily on the first.
If your period does not come after Lindinet, when after finishing taking the entire package, the next one is started. This also happens; there is no need to panic if all application rules are followed. My period will start in the next cycle; for some reason my body didn’t have time to adapt this month. But in the case when critical days are delayed up to 50 - 60 days from the previous ones, you should undergo examination by specialists. It may be necessary to make some adjustments to the reception.

Is it possible to get pregnant while taking it?

Even when taking birth control, everyone is concerned about whether the method is as reliable as described. Indeed, if there are no periods after Lindinet, it’s worth thinking about pregnancy, especially in some cases. These include the following:

Skipping pills, especially if the break is more than 12 hours or several pills at once. Also, the effectiveness of contraceptives decreases if the instructions for use are violated several times during one cycle.
If on one of the days of taking the girl there was nausea, vomiting or diarrhea, as well as any digestive disorders that could lead to incomplete absorption of the drug in the gastrointestinal tract.
If, while taking the pills for health reasons, the girl was taking other medications. This is especially true for antibiotics (ampicillin, rifampicin and others), some laxatives (senna extract), antifungals (fluconazole, etc.), certain herbal medicines (for example, St. John's wort). Therefore, if treatment is necessary, you should carefully familiarize yourself with the interaction of the drugs and their influence on each other, and even better, use additional contraceptives throughout the entire therapy and seven days after its completion.

To avoid getting into an uncomfortable position and causing harm to your health, you should carefully study the instructions before starting to take the drug and, in emergency situations, act according to them. And if you have any doubts, you should consult a doctor.

Lindinet is a combined monophasic contraceptive drug that exists in two variations - 0.02 and 0.03 mg of the estrogen component. Suitable for young and active girls. If the rules of use are followed, it helps to achieve almost 100% protection against pregnancy. Happens while taking Lindinet, spotting, as well as some other malfunctions. In most cases, the menstrual cycle returns to normal within 2 to 3 months. If in doubt, consult a doctor.

Numerous reviews from women speak about discharge when taking Lindinet 20. As a rule, this is a brown daub at different periods of the cycle. Today we will talk about whether the described phenomenon is normal, and whether it is worth stopping the drug and choosing another contraceptive.

What is Lindinet 20?

A combined type oral contraceptive, the tablet contains estrogen-like and gestagenic chemical compounds. Lindinet suppresses ovulation, thickens cervical mucus and changes the quality of the endometrium, which together prevents conception and the fixation of the fertilized egg in the uterus. The number 20 in this case indicates the concentration of ethinyl estradiol, respectively, in Lindinet there is 30 more of it.

If ovulation does not occur, then menstruation in its natural form is impossible. However, a special dosage regimen leads to monthly bleeding. For 21 days you need to take one tablet, while the rest of the week of the standard cycle is taken as a break. In the absence of the active substances of the drug, withdrawal bleeding occurs, which is similar to menstruation.

Like other combined contraceptives, Lindinet 20 is used to treat various gynecological diseases that develop against the background of hormonal disorders. In addition, the drug is used if a woman has long and painful menstruation or an unstable cycle.

Lindinet 20 is often prescribed without tests for hormone levels, or in situations where test results do not show significant changes. The drug contains a minimal amount of active substances and in a combination that does not harm the female body. However, in some cases, stronger agents or with a special ratio of estrogens and gestagens are required.

The main effects of Lindinet 20 on a woman’s body:

Prevention of pregnancy if taken daily for 21 days and preferably at the same time with a break of up to 1 week at the end of the cycle. Packages of 21 or 63 pills are produced, which corresponds to the dosage schedule.
Regression of ovarian cysts, hormone-dependent tumors in the uterus.
Getting rid of endometriosis and endometrial hyperplasia.
Normalization of the state of the endocrine system with an excess of male hormones with corresponding symptoms - acne, hair loss on the head and increased hair growth throughout the body.
Normalization of the cycle occurs as a result of withdrawal bleeding, which occurs in response to the absence of the drug at the end of the cycle. “Menstruations” are regular and moderate.

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Expert opinion

Olga Yurievna Kovalchuk

Doctor, expert

Unfortunately, women often choose oral contraceptives on their own, based on reviews of other patients or the price of the drug. This is fundamentally wrong. There are no good or bad pills. There are suitable ones and not so suitable ones. In addition, you can express your desires regarding cost or other aspects to the gynecologist so that he can select a drug that suits your pocket.

What kind of discharge occurs when taking Lindinet 20?

Any combined contraceptive agent causes changes in the body. For some time, the so-called adaptation to the drug occurs. The timing of its completion is individual, as is the intensity and set of symptoms. Mostly, patients note the following manifestations in the first 2-3 months of using Lindinet 20:

Scanty and on the eve of menstruation;
Long menstruation for about 7-9 days with spotting at the beginning and end;
Sometimes leucorrhoea may have a pink tint;
Sexual desire decreases or disappears;
Migraine-like headache attacks occur;
Inflammation in the vagina with itching and redness;
Enlargement and hardening of the mammary glands combined with mild pain;
Edema and weight gain.

Cervical secretion thickens due to the use of oral contraceptives and therefore does not occur. Basically, a woman is afraid of bloody leucorrhoea on different days of the cycle. When there is little blood, the liquid has a pinkish or brown tint and will only smear. Sometimes the leucorrhoea is quite dark and may contain some clots.

In the future, the cycle depends on the use of Lindinet. Your period will appear during the break. The last 21st pill is the end of the cycle. The start of treatment is therefore scheduled for the period of menstruation.

Why does bleeding occur when using Lindinet 20?

The reason lies in the influence of hormones on the formation of the endometrium. The intrauterine layer is usually very loose and is necessary for consolidation - implantation of the embryo and its subsequent nutrition. The active substances of the drug change the quality of the endometrium. It becomes denser and thinner, the fertilized egg will no longer be able to catch on here. As we know, the intrauterine mucosa is a jelly-like substance filled with blood. As a result, when it changes, bleeding occurs at different periods of the cycle. This is not menstruation, and while the fluid comes out, it will have time to coagulate, acquiring a dark shade.

If, while using the Lindinet 20 contraceptive, prolonged and fairly heavy bleeding occurs, then you should consult a gynecologist. Perhaps the drug is not suitable in this case and a more concentrated hormonal agent is required, for example, Lindinet 30.

When using a contraceptive drug there should not be the following symptoms:

Foul odor of discharge;
Pulling in the lower abdomen;
Heavy bleeding except during menstruation;
Temperature increase.

Attention! Missing doses for more than 12 hours may result in bleeding. Therefore, it is very important to use the product at the same hour every day. That does not apply to the week-long rest period at the end of the cycle.

When does addiction to the drug end?

The duration and nature of adaptation vary from person to person. Gynecologists consider it normal for bloody spotting to occur within 3-4 cycles. Provided that the situation gradually stabilizes and the symptoms subside. Usually, there is a prolongation of the menstrual period in the first month of taking Lindinet 20, as well as spotting on other days. In cycle 2, rare, scanty brown discharge occurs. And then the situation returns to normal.

If there has been a dark spot for 5-6 months when using Lindinet

Of course, in such a situation, only a doctor can make a decision. The best option would be to consult a gynecologist-endocrinologist or reproductive specialist and analyze the level of sex hormones. If for some reason it is impossible to visit an antenatal clinic, it is permissible to try Lindinet 30. However, again you will have to wait 1-2 cycles until the situation stabilizes and adaptation takes place.

Attention! If a drug is prescribed for treatment based on the results of histology, then there can be no talk of any independent replacement.

Unusual situation - discharge occurred after long-term use of Lindinet

Judging by the reviews of women, this really happens. Doctors attribute this to hormonal changes. The endocrine system is affected not only by oral contraceptives, but also by various circumstances in a woman’s life:

Stressful situations;
Use of other medications;
Diseases;
Moving, different climate;
Sudden changes in physical activity, work;
Diets, fasting;
Obesity or dystrophy;
And other.

In such a situation, a control examination by a gynecologist is necessary, and, possibly, correction of contraception.

Interesting information about birth control pills

Not everyone knows that there is a limited number of eggs in the female body. They are not produced throughout life, like sperm. When the supply runs out, the woman becomes infertile, menstruation stops, and menopause begins. Accordingly, the body almost ceases to produce female hormones. Namely, they provide luxurious hair and skin, rounded body shapes and other aspects of female beauty.

By taking combined contraceptives, the patient blocks the flow of eggs, delays the onset of menopause and maintains youth and attractiveness. Therefore, properly selected drugs can not only get rid of unwanted pregnancy, abortion, diseases, but also improve the quality of life.

In addition, it is during menopause that the risk of cancer arises, and hormonal therapy helps to avoid such danger.

Carefully! It is worth remembering that if you already have tumors, taking Lindinet or other birth control pills is dangerous. As with increased blood clotting and some other problems.

Conclusion

Doctors advise choosing contraceptives in the gynecologist's office, and not on your own. In addition, you should report any sensations to your doctor. Only a specialist, based on analyzes and other facts, can choose a safe and useful remedy.

Recently, more and more women are choosing Lindinet 20 as an oral contraceptive. It is believed that this hormonal drug has a fairly gentle effect on the female body. According to statistics, the number of people who become pregnant while taking a contraceptive varies within 0.05%. Despite this, you should approach its use with the utmost seriousness. Feedback from the women and specialists who took it will help with this.

Lindinet 20: features of the drug

Lindinet 20 is a film-coated tablet. They are sold in separate blisters and are designed for specific courses of administration. Moreover, all tablets have the same doses of hormones.

The effect of the drug is due to the presence of ethinyl estradiol and gestodene in its composition. The first is a synthetic analogue of a hormone that affects the menstrual cycle. How the drug works: its components affect ovulation. They also make the mucus in the cervix more viscous. Due to this, sperm cannot continue moving towards the egg.

The drug is interesting because it can have a positive therapeutic effect on the female body. It manifests itself in the fact that menstruation becomes less painful. The cycle is also being established. Lindinet 20 is believed to have a preventive effect. In particular, it can prevent the occurrence of fibroids and ovarian cancer.

How to take Lindinet 20?

The main feature of the drug is the method of application. The tablets in the blaster are numbered. You need to drink them in this order, 1 piece per day. It's better to choose the same time. There is a nuance. Oral hormonal contraceptives are thought to increase appetite. Therefore, it is better to drink them in the evening, when you are less hungry. Some doctors believe that the optimal time is 9 hours, since at this time hormones begin to be better absorbed. Take the drug according to the following regimen:

Start drinking Lindinet 20 from day 1 to day 5 of the menstrual cycle. On the first days of taking the medication, menstruation may stop. Don't be alarmed. This is the body's reaction.
In the first 14 days of taking the contraceptive, non-hormonal methods of contraception should be used. This is due to the fact that the contraceptive effect may not occur at this time. This reaction is associated with the absorption of hormones and their effect on the body.
Then take 1 tablet for 21 days. Then you need to take a 7-day break. During this period, your period may begin. During this period of time, you can do without other methods of contraception if you continue the course.
Resume drinking Lindinet strictly on the 8th day of the break. This is done even if you have started your period.
The drug has a number of features. They are often related to how to take Lindinet 20 after other contraceptives. Dosage regimens depend on the course of previous medications. If it contained 28 tablets, then Lindinet 20 is taken the next day. It happens that contraceptives are designed for 21 days. In this case, you can take Lindinet 20 immediately the day after the last tablet. It is also allowed to take a 7-day break and drink it on the 8th day.
A separate scheme exists if you stick on a hormonal contraceptive patch or put on a ring. Then you can start drinking Lindinet 20 after you take it off. Or they drink it on the day when they need to be replaced.
The instructions for the drug also indicate how it should be taken if you “miss” tablets. If this happened between days 1 and 7, then the drug should be taken as soon as possible. A double dose is allowed. By the way, it has the desired effect only for 12 hours. In the next week you will have to take additional protection. In the period from 8 to 14 days they do the same. If there were no missed pills in the previous week, then you don’t have to use other methods of protection. The same rule applies if you miss a period of 15-21 days.

Lindinet 20: side effects

The side effects of Lindinet 20 can be scary for some women. The manufacturer states that in some cases the drug can also lead to hearing loss! The main unpleasant symptoms from taking the drug include:

Deterioration of the condition - headaches up to migraines, nausea, weakness occur. A sharp change in mood, and even depression, is possible.
Problems with skin and hair - hair may begin to fall out. Eczema or rash appears on the skin.
Changes in the reproductive system are also possible. Discharge or inflammation may begin. Sometimes women's sexual activity is greatly reduced.
The digestive system reacts with stomach pain and even the occurrence of ulcerative colitis!
Decreased vision is also possible.
This drug should not be taken by diabetics, women who have problems with blood clots, those with liver tumors, jaundice, during pregnancy and lactation, and in a number of other cases.

Lindinet 20: reviews from doctors

Lindinet 20 is a special drug. The instructions for it say that it cannot be prescribed independently. If you want to switch to this contraceptive, then first you need to contact a gynecologist. He will conduct a routine examination and prescribe the necessary tests. The drug is prescribed only on the basis of diagnosis!

The reviews of doctors regarding the action of Lindinet 20 deserve special attention. There are opinions that the drug is “capricious” in addition. This means that there are cases when it is difficult for a woman’s body to perceive it. This manifests itself, among other things, in the manifestation of some side effects. The woman simply feels bad. The condition worsens to the point that bright red discharge occurs, the temperature rises and severe weakness.

Equally important are the reviews of Lindinet from the 20 women taking it. There are differing opinions about this drug online. This is how you can find references to strong side effects. Some people experience spotting and pain in the lower abdomen that radiates to the lower back. Those who are not suitable for Lindinet 20 may also suffer from nausea, even to the point of not eating. It happens that the drug causes migraines.

Some women, on the contrary, experience positive side effects due to taking Lindinet 20. Thus, representatives of the fair sex, in some cases, according to reviews, are pleased with enlarged breasts. In some cases, it becomes 1-1.5 sizes larger! Weight normalization is also noted. One of the women in reviews of Lindinet 20 wrote that she started taking it when her daughter was 6 months old. At that moment, with a height of 165 cm, she weighed 80 kg. As a result, after six months of taking it, her weight decreased to 68 kg!

Lindinet 20 can be used only after consulting a gynecologist. It is prescribed based on the results of examination and tests. They drink the contraceptive from days 1 to 5 of the 21-day cycle. Then they take a break for 7 days and resume taking it on the 8th day. In the first 14 days you need to use additional contraception. Reviews for the drug vary. In some cases, the woman’s body rejects it. This causes severe side effects.

P No. 015122/01

Trade name of the drug:

Lindinet 20

International nonproprietary name:

ethinylestradiol + gestodene

Dosage form:

film-coated tablets.

Compound:

active substance: ethinyl estradiol - 0.02 mg and gestodene - 0.075 mg
Excipients: in the core: Sodium calcium edetate - 0.065 mg; magnesium stearate - 0.200 mg; colloidal silicon dioxide - 0.275 mg; povidone - 1,700 mg; corn starch - 15,500 mg; lactose monohydrate 37.165 mg;
in shell: Quinoline yellow dye E 104 (D+S Yellow No. 10 E 104) - 0.00135 mg; povidone - 0.171 mg; titanium dioxide - 0.46465 mg; macrogol 6000 - 2.23 mg; talc - 4.242 mg; calcium carbonate - 8.231 mg; sucrose - 19.66 mg.

Description:

Round, biconvex, film-coated tablets, light yellow in color. On the break it is white or almost white with a light yellow edging, both sides without an inscription.

Pharmacotherapeutic group:

contraceptive (estrogen + progestogen)

ATX code:

G03AB06

Pharmacological properties

Pharmacodynamics
A combined agent, the effect of which is determined by the effects of the components included in its composition. Inhibits the pituitary secretion of gonadotropic hormones. The contraceptive effect of the drug is associated with several mechanisms. The estrogenic component of the drug is a highly effective oral drug - ethinyl estradiol (a synthetic analogue of estradiol, which participates together with the corpus luteum hormone in the regulation of the menstrual cycle). The gestagenic component is a derivative of 19-nortestosterone - gestodene, which is superior in strength and selectivity to not only the natural hormone of the corpus luteum progesterone, but also modern synthetic gestagens (levonorgestrel, etc.). Due to its high activity, gestodene is used in very low dosages, in which it does not exhibit androgenic properties and has virtually no effect on lipid and carbohydrate metabolism.
Along with the indicated central and peripheral mechanisms that prevent the maturation of an egg capable of fertilization, the contraceptive effect is due to a decrease in the susceptibility of the endometrium to the blastocyst, as well as an increase in the viscosity of the mucus located in the cervix, which makes it relatively impenetrable for sperm.
In addition to the contraceptive effect, the drug, when taken regularly, also has a therapeutic effect, normalizing the menstrual cycle and helping to prevent the development of a number of gynecological diseases, incl. tumor nature.

Pharmacokinetics
Gestodene:
Suction: When taken orally, it is quickly and completely absorbed. After taking one dose, the maximum plasma concentration is measured after an hour and is 2-4 ng/ml. Bioavailability is about 99%.
Distribution: binds to albumin and sex hormone binding globulin (SHBG). 1-2% is in a free state, 50-75% is specifically associated with SHBG. The increase in SHBG levels caused by ethinyl estradiol affects the level of gestodene, leading to an increase in the SHBG-bound fraction and a decrease in the albumin-bound fraction. The volume of distribution of gestodene is 0.7-1.4 l/kg.
Metabolism: Corresponds to the steroid metabolism pathway. Average plasma clearance: 0.81.0 ml/min/kg.
Removal: Blood levels decrease in two stages. Half-life in the final phase is 1220 hours. It is excreted exclusively in the form of metabolites: 60% in urine, 40% in feces. The half-life of metabolites is approximately 1 day.
Stable concentration: The pharmacokinetics of gestodene largely depends on the level of SHBG. Under the influence of ethinyl estradiol, the concentration of SHBG in the blood increases three times; with daily use of the drug, the level of gestodene in plasma increases three to four times and in the second half of the cycle reaches a state of saturation.
Ethinyl estradiol:
Suction: When taken orally, it is absorbed quickly and almost completely. The maximum concentration in the blood is measured after 1-2 hours and is 30-80 pg/ml. Absolute bioavailability ≈60% due to pre-systemic conjugation and primary metabolism in the liver.
Distribution: easily enters into a nonspecific relationship with blood albumin (about 98.5%) and causes an increase in SHBG levels. The average volume of distribution is 5-18 l/kg.
Metabolism: carried out mainly due to aromatic hydroxylation with the formation of large quantities of hydroxylated and methylated metabolites, partly in free, partly in conjugated form (glucuronides and sulfates). Plasma clearance ≈5-13 ml/min/kg.
Removal: Serum concentration decreases in two stages. The half-life in the second phase is ≈16-24 hours. It is excreted exclusively in the form of metabolites in a 2:3 ratio with urine and bile. The half-life of metabolites is ≈1 day.
Stable concentration: A stable concentration is established by 3-4 days, while the level of ethinyl estradiol is 20% higher than after taking a single dose.

Indications for use

Contraception.

Contraindications

pregnancy or suspicion of it;
lactation;
the presence of severe or multiple risk factors for venous or arterial thrombosis, incl. complicated lesions of the valvular apparatus of the heart, atrial fibrillation, diseases of the cerebral vessels or coronary arteries; uncontrolled moderate or severe arterial hypertension with blood pressure 160/100 mmHg or more);
precursors of thrombosis (including transient ischemic attack, angina), including a history;
migraine with focal neurological symptoms, including a history;
venous or arterial thrombosis/thromboembolism (including deep vein thrombosis of the leg, pulmonary embolism, myocardial infarction, stroke) currently or in history,
the presence of venous thromboembolism in relatives;
major surgery with prolonged immobilization;
diabetes mellitus (with the presence of angiopathy);
pancreatitis (including a history), accompanied by severe hypertriglyceridemia;
dyslipidemia;
severe liver diseases, cholestatic jaundice (including during pregnancy), hepatitis, incl. history (before normalization of functional and laboratory parameters and within three months after these parameters return to normal);
jaundice due to taking drugs containing steroids;
gallstone disease currently or in history;
Gilbert, Dubin-Johnson, Rotor syndrome;
liver tumors (including history);
severe itching, otosclerosis or progression of otosclerosis during a previous pregnancy or while taking glucocorticosteroids;
hormone-dependent malignant neoplasms of the genital organs and mammary glands (including suspicion of them);
vaginal bleeding of unknown etiology;
smoking over the age of 35 (more than 15 cigarettes per day);
individual hypersensitivity to the drug or its components.

Carefully
Conditions that increase the risk of developing venous or arterial thrombosis/thromboembolism: age over 35 years, smoking, hereditary predisposition to thrombosis (thrombosis, myocardial infarction or cerebrovascular accident at a young age in one of the immediate family); hemolytic uremic syndrome, hereditary angioedema, liver disease; diseases that first appeared or worsened during pregnancy or against the background of previous use of sex hormones (including porphyria, herpes of pregnant women, minor chorea (Sydenham's disease), Sydenham's chorea, chloasma); obesity (body mass index more than 30 kg/m2), dyslipoproteinemia, arterial hypertension, migraine, epilepsy, valvular heart disease, atrial fibrillation, prolonged immobilization, extensive surgery, surgery on the lower extremities, severe trauma, varicose veins and superficial thrombophlebitis, postpartum period (non-lactating women 21 days after birth; nursing women after completion of the lactation period), the presence of severe depression, incl. history, changes in biochemical parameters (activated protein C resistance, hyperhomocysteinemia, antithrombin III deficiency, protein C or S deficiency, antiphospholipid antibodies, including antibodies to cardiolipin, lupus anticoagulant).
Diabetes mellitus not complicated by vascular disorders, systemic lupus erythematosus (SLE), Crohn's disease, ulcerative colitis, sickle cell anemia; hypertriglyceridemia (including family history), acute and chronic liver diseases.

Pregnancy and lactation

The use of the drug during pregnancy and breastfeeding is contraindicated.

Directions for use and doses

Take 1 tablet per day for 21 days, if possible at the same time of day. Then, after taking a 7-day break from taking pills, resume oral contraception (i.e. 4 weeks after taking the first pill, on the same day of the week). During the 7-day break, uterine bleeding occurs as a result of hormone withdrawal.
First tablet: Taking Lindinet 20 should start from the first to the fifth day of the menstrual cycle.
Transition from a combined oral contraceptive to taking Lindinet 20: It is recommended to take the first tablet of Lindinet 20 after taking the last hormone-containing tablet of the previous drug, on the first day of withdrawal bleeding.
Transition from progestogen-containing drugs (“mini” tablets, injections, implants) to taking Lindinet 20: The transition from “mini” pills can be started on any day of the menstrual cycle; in the case of an implant - the day after its removal; in case of injections - on the eve of the last injection.
In this case, in the first 7 days of taking Lindinet 20, it is necessary to use an additional method of contraception.
Taking Lindinet 20 after an abortion in the first trimester of pregnancy:
You can start taking a contraceptive immediately after an abortion, and there is no need to use an additional method of contraception.
Taking Lindinet 20 after childbirth or after an abortion in the second trimester of pregnancy: You can start taking the contraceptive 21-28 days after childbirth or abortion in the second trimester of pregnancy. If you start taking a contraceptive later, in the first 7 days, it is necessary to use an additional, barrier method of contraception. In the case where sexual intercourse took place before the start of contraception, before starting to take the drug, you should exclude the presence of a new pregnancy or wait until the next menstruation.
Missed pills
If the next scheduled dose is missed, then you should make up for the missed dose as soon as possible. If the delay does not exceed 12 hours, the contraceptive effect of the drug is not reduced, and there is no need to use an additional method of contraception. The remaining tablets are taken as usual.
If there is a delay of more than 12 hours, the contraceptive effect may decrease. In such cases, you should not make up for the missed dose, continue taking the drug as usual, but in the next 7 days you must use an additional method of contraception. If at the same time there are less than 7 tablets left in the package, then take the tablets from the next package without taking a break. In such cases, uterine withdrawal bleeding occurs only after the completion of the second package; While taking tablets from the second package, spotting or breakthrough bleeding is possible.
If, upon completion of taking the pills from the second package, withdrawal bleeding does not occur, then pregnancy should be ruled out before continuing to take the contraceptive.
Measures to be taken in case of vomiting and diarrhea:
If vomiting occurs in the first 3-4 hours after taking another tablet, the tablet is not completely absorbed. In such cases, you should act in accordance with the instructions described in the section “Missed tablets”.
If the patient does not want to deviate from her usual contraceptive regimen, the missed pills should be taken from another package.
Delay of menstruation and acceleration of the onset of menstruation:
In order to delay menstruation, pills from a new package are started to be taken without taking a break. Menstruation can be delayed at will until all the tablets from the second package are gone. If menstruation is delayed, breakthrough or spotting uterine bleeding is possible. You can return to your usual pill intake after a 7-day break.
In order to achieve an earlier onset of menstrual bleeding, you can shorten the 7-day break by the desired number of days. The shorter the break, the more likely it is that breakthrough or spotting bleeding will occur while taking tablets from the next package (similar to cases with delayed menstruation).

Side effect

Side effects that require immediate discontinuation of the drug:

arterial hypertension;
hemolytic-uremic syndrome;
porphyria;
hearing loss due to otosclerosis.

Rarely found: arterial and venous thromboembolism (including myocardial infarction, stroke, deep vein thrombosis of the lower extremities, pulmonary embolism); exacerbation of reactive systemic lupus erythematosus.
Very rare: arterial or venous thromboembolism of the hepatic, mesenteric, renal, retinal arteries and veins; Sydenham's chorea (passing after discontinuation of the drug).
Other side effects, less severe, but more common. The advisability of continuing to use the drug is decided individually after consultation with a doctor, based on the benefit/risk ratio.

Reproductive system: acyclic bleeding/spotting from the vagina, amenorrhea after discontinuation of the drug, changes in the state of vaginal mucus, development of inflammatory processes in the vagina (eg candidiasis), changes in libido.
Mammary gland: tension, pain, breast enlargement, galactorrhea.
Gastrointestinal tract and hepato-biliary system: nausea, vomiting, diarrhea, epigastric pain, Crohn's disease, ulcerative colitis, hepatitis, liver adenoma, occurrence or exacerbation of jaundice and/or itching associated with cholestasis, cholelithiasis.
Leather: erythema nodosum/exudative, rash, chloasma, increased hair loss.
central nervous system: headache, migraine, mood changes, depression.
Metabolic disorders: fluid retention in the body, change (increase) in body weight, increased levels of triglycerides and blood sugar, decreased tolerance to carbohydrates.
Sense organs: hearing loss, increased sensitivity of the cornea when wearing contact lenses.
Others: allergic reactions.

Overdose

Taking large doses of the contraceptive was not accompanied by the development of severe symptoms. Signs of overdose: nausea, vomiting, slight vaginal bleeding in young girls. There is no specific antidote, treatment is symptomatic.

Interaction with other drugs

The contraceptive effect of oral contraceptives is reduced with simultaneous use of rifampicin, breakthrough bleeding and menstrual irregularities become more frequent.
Similar, however, less studied interactions exist between contraceptives and carbamazepine, primidone, barbiturates, phenylbutazone, phenytoin and, presumably, griseofulvin, ampicillin and tetracyclines. During treatment with the above drugs, it is recommended to use an additional method of contraception (condom, spermicidal gel) simultaneously with oral contraception. After completing the course of treatment, the use of an additional method of contraception should be continued for 7 days, in the case of treatment with rifampicin - for 4 weeks.
Interactions associated with drug absorption: During diarrhea, the absorption of hormones is reduced due to increased intestinal motility. Any drug that shortens the time a hormonal agent remains in the large intestine leads to low concentrations of the hormone in the blood.
Interactions related to drug metabolism:
Intestinal wall: Drugs that undergo sulfation in the intestinal wall like ethinyl estradiol (eg ascorbic acid) inhibit metabolism in a competitive manner and increase the bioavailability of ethinyl estradiol.
Metabolism in the liver: Inducers of microsomal liver enzymes reduce the level of ethinyl estradiol in the blood plasma (rifampicin, barbiturates, phenylbutazone, phenytoin, griseofulvin, topiramate, hydantoin, felbamate, rifabutin, oscarbazepine). Liver enzyme blockers (itraconazole, fluconazole) increase the level of ethinyl estradiol in the blood plasma.
Effect on intrahepatic circulation: Some antibiotics (eg, ampicillin, tetracycline), by interfering with the intrahepatic circulation of estrogens, reduce the level of ethinyl estradiol in plasma.
Effect on the metabolism of other drugs: By blocking liver enzymes or accelerating conjugation in the liver, mainly increasing glucuronidation, ethinyl estradiol affects the metabolism of other drugs (eg, cyclosporine, theophylline), leading to an increase or decrease in their plasma concentrations.
The simultaneous use of St. John's wort preparations is not recommended ( Hypericum perforatum) with Lindinet 20 tablets due to a possible decrease in the contraceptive effect of the active substance of the contraceptive, which may be accompanied by breakthrough bleeding and unwanted pregnancy. St. John's wort activates liver enzymes; after stopping the use of St. John's wort, the effect of enzyme induction may persist for the next 2 weeks.
Concomitant use of ritonavir and a combined contraceptive was associated with a 41% decrease in the mean AUC of ethinyl estradiol. During treatment with ritonavir, it is recommended to use a drug with a high content of ethinyl estradiol or use a non-hormonal method of contraception. It may be necessary to adjust the dosage regimen when using hypoglycemic agents, because Oral contraceptives may decrease carbohydrate tolerance and increase the need for insulin or oral antidiabetic agents.

special instructions

Before starting to use the drug, it is recommended to collect a detailed family and personal history and subsequently every 6 months. undergo a general medical and gynecological examination (examination by a gynecologist, examination of a cytological smear, examination of the mammary glands and liver function, control of blood pressure (BP), cholesterol concentrations in the blood, urine analysis). These studies must be repeated periodically, due to the need for timely identification of risk factors or contraindications that have arisen.
The drug is a reliable contraceptive drug: the Pearl index (an indicator of the number of pregnancies that occurred during the use of a contraceptive method in 100 women over 1 year) when used correctly is about 0.05. Due to the fact that the contraceptive effect of the drug from the start of administration is fully manifested by the 14th day, in the first 2 weeks of taking the drug, it is recommended to additionally use non-hormonal methods of contraception.
In each case, before prescribing hormonal contraceptives, the benefits or possible negative effects of their use are individually assessed. This issue must be discussed with the patient, who, after receiving the necessary information, will make the final decision on the preference for hormonal or any other method of contraception. The woman's health condition must be carefully monitored. If any of the following conditions/diseases appear or worsen while taking the drug, you must stop taking the drug and switch to another, non-hormonal method of contraception:

diseases of the hemostatic system.
conditions/diseases predisposing to the development of cardiovascular and renal failure.
epilepsy
migraine
the risk of developing an estrogen-dependent tumor or estrogen-dependent gynecological diseases;
diabetes mellitus not complicated by vascular disorders;
severe depression (if depression is associated with impaired tryptophan metabolism, then vitamin B6 can be used for correction);
sickle cell anemia, since in some cases (for example, infections, hypoxia), estrogen-containing drugs in this pathology can provoke thromboembolism.
the appearance of abnormalities in laboratory tests assessing liver function.

Thromboembolic diseases
Epidemiological studies have shown that there is an association between taking oral hormonal contraceptives and an increased risk of arterial and venous thromboembolic diseases (including myocardial infarction, stroke, deep vein thrombosis of the lower extremities, pulmonary embolism).
An increased risk of venous thromboembolic diseases has been proven, but it is significantly less than during pregnancy (60 cases per 100 thousand pregnancies). When using oral contraceptives, arterial or venous thromboembolism of the hepatic, mesenteric, renal or retinal vessels is very rarely observed.
The risk of arterial or venous thromboembolic disease increases:

with age;
when smoking (heavy smoking and age over 35 years are risk factors);
if there is a family history of thromboembolic diseases (for example, parents, brother or sister). If a genetic predisposition is suspected, it is necessary to consult a specialist before using the drug.
for obesity (body mass index above 30 kg/m2);
with dislipoproteinemia;
with arterial hypertension;
for diseases of the heart valves complicated by hemodynamic disorders,
with atrial fibrillation;
with diabetes mellitus complicated by vascular lesions;
with prolonged immobilization, after major surgery, after surgery on the lower extremities, after severe trauma.

In these cases, a temporary cessation of use of the drug is assumed: it is advisable to stop no later than 4 weeks before surgery, and resume no earlier than 2 weeks after remobilization.
The risk of venous thromboembolic diseases increases in women after childbirth.
Diseases such as diabetes mellitus, systemic lupus erythematosus, hemolytic-uremic syndrome, Crohn's disease, ulcerative colitis, and sickle cell anemia increase the risk of developing venous thromboembolic diseases.
Biochemical abnormalities such as resistance to activated protein C, hyperchromocysteinemia, protein C and S deficiency, antithrombin III deficiency, and the presence of antiphospholipid antibodies increase the risk of arterial or venous thromboembolic diseases.
When assessing the benefit/risk ratio of taking the drug, it must be borne in mind that targeted treatment of this condition reduces the risk of thromboembolism. Signs of thromboembolism are:

sudden chest pain that radiates to the left arm,
sudden shortness of breath,
any unusually severe headache that continues for a long time or appears for the first time, especially when combined with sudden complete or partial loss of vision or diplopia, aphasia, dizziness, collapse, focal epilepsy), weakness or severe numbness of half the body, movement disorders, severe unilateral pain in the calf muscle, acute abdomen).

Tumor diseases
Some studies have reported an increased incidence of cervical cancer in women who took hormonal contraceptives for a long time, but the results of the studies are inconsistent. Sexual behavior, infection with the human papillomavirus and other factors play a significant role in the development of cervical cancer.
A meta-analysis of 54 epidemiological studies found that there was a relative increase in the risk of breast cancer among women taking oral hormonal contraceptives, but the higher detection rate of breast cancer may have been associated with more regular medical screening. Breast cancer is rare among women under 40, whether they are taking hormonal birth control or not, and increases with age. Taking pills can be considered one of many risk factors. However, women should be made aware of the possible risk of developing breast cancer based on a benefit-risk assessment (protection against ovarian, endometrial and colon cancer).
There are few reports of the development of benign or malignant liver tumors in women taking hormonal contraceptives for a long time. This should be kept in mind when diagnosing abdominal pain, which may be associated with an increase in liver size or intra-abdominal bleeding.
The woman should be warned that the drug does not protect against HIV infection (AIDS) and other sexually transmitted diseases.
The effectiveness of the drug may decrease in the following cases:: missed pills, vomiting and diarrhea, simultaneous use of other drugs that reduce the effectiveness of birth control pills.
If the patient is simultaneously taking another drug that may reduce the effectiveness of birth control pills, additional methods of contraception should be used.
The effectiveness of the drug may decrease if, after several months of their use, irregular, spotting or breakthrough bleeding appears, in such cases it is advisable to continue taking the tablets until they run out in the next package. If at the end of the second cycle menstrual-like bleeding does not begin or acyclic bleeding does not stop, stop taking the pills and resume it only after pregnancy has been ruled out.
Chloasma
Chloasma can occasionally occur in women who have a history of it during pregnancy. Those women who are at risk of developing chloasma should avoid contact with sunlight or ultraviolet radiation while taking the pills.
Changes in laboratory parameters
Under the influence of oral contraceptive pills - due to the estrogen component - the level of some laboratory parameters (functional indicators of the liver, kidneys, adrenal glands, thyroid gland, hemostasis indicators, levels of lipoproteins and transport proteins) may change.
After acute viral hepatitis, it should be taken after normalization of liver function (no earlier than 6 months). In case of diarrhea or intestinal disorders, vomiting, the contraceptive effect may decrease (without stopping the drug, it is necessary to use additional non-hormonal methods of contraception). Women who smoke have an increased risk of developing vascular diseases with serious consequences (myocardial infarction, stroke). The risk depends on age (especially in women over 35 years of age) and on the number of cigarettes smoked. During lactation, milk secretion may decrease; in small quantities, the components of the drug are excreted in breast milk.

Effect of the drug on the ability to drive a car and operate machinery

Studies have not been conducted to study the possible effect of Lindinet 20 on the ability to drive a car or other machines.

Release form

Film-coated tablets.
21 tablets in a blister made of PVC/PVDC film and aluminum foil.
1 or 3 blisters in a cardboard box with instructions for use.

Storage conditions

Store in a dry place, protected from light, at a temperature not exceeding 25°C.
Keep out of the reach of children!

Best before date

3 years.
Use the drug only taking into account the expiration date indicated on the packaging.

Conditions for dispensing from pharmacies

Dispensed by prescription.

Manufacturer

JSC "Gedeon Richter", Hungary
1103 Budapest, st. Gemrei 19-21, Hungary

Send consumer complaints to the address of the Moscow Representative Office:
119049 Moscow, 4th Dobryninsky lane, building 8

Latin name: Lindynette
ATX code: G03AA10
Active substance: Ethinyl estradiol
Manufacturer: Gedeon Richter, Hungary
Conditions for dispensing from a pharmacy: On prescription

Lindinet 20 is one of the low-hormone oral contraceptives.

Indications for use

Lindinet 20 tablets are taken for contraceptive purposes, as well as to regulate impaired menstrual function.

Compound

One hormonal contraceptive tablet contains two main components, which are ethinyl estradiol and gestodene, their mass fraction is 0.02 mg and 0.075 mg, respectively.

Additionally there are the following substances:

Povidone
Magnesium stearate
Corn starch
Silicon dioxide in colloidal form
Lactose monohydrate
Sodium calcium edetate.

Medicinal properties

A contraceptive based on ethinyl estradiol and gestodene inhibits the process of synthesis of gonadotropic hormones by the pituitary gland, which helps slow down the maturation of follicles.

The estrogen component of birth control pills is represented by ethinyl estradiol, which is one of the synthetic analogues of the hormone estradiol produced in the human body, which is actively involved in the regulation of menstrual function along with progesterone.

Gestodene is the second component of the contraceptive; it is classified as a derivative of 19-nortestosterone; in terms of its potency, it is significantly superior to both the natural hormone, progesterone, and its synthetic analogue, levonorgestrel. Due to the fact that the activity of this gestagenic component of Lindinet is quite high, it is used in low doses. Due to this, there is no significant effect on the metabolism of fats and carbohydrates, and its androgenic properties do not appear.

The action of the contraceptive is associated with the work of both central and peripheral mechanisms that inhibit the process of follicle maturation, thereby reducing the susceptibility of the endometrial uterine layer to the blastocyst itself. At the same time, the viscosity of the discharge (namely cervical mucus) increases, which significantly reduces the likelihood of conception.

If you drink Lindinet 20 constantly (as the description for the drug indicates), you can observe the therapeutic effect of the contraceptive - the circulatory cycle is normalized, and the risk of developing certain gynecological ailments, including cancer, is reduced.

Ethinyl estradiol is almost completely absorbed by the mucous membranes of the gastrointestinal tract. 1-2 after taking the tablets (according to the instructions), its highest concentration in the blood is observed. The bioavailability rate is 60%. Communication with albumin is 98.5%.

As a result of aromatic hydroxylation, the formation of methylated and hydroxylated metabolites occurs. The elimination process involves the renal system and intestines; the half-life is 24 hours. In this case, a stable level of ethinyl estradiol is recorded on days 3-4.

Gestodene also quickly undergoes the process of absorption in the gastrointestinal tract; the highest levels of this substance in the blood are achieved after 60 minutes. The bioavailability of the gestagenic component of the drug reaches 99%.

The amount of gestodene in the blood decreases slowly, the half-life of metabolic products is 24 hours. A stable level of gestodene is observed in the 2nd half of the MC.

Release form

Hormonal pills are round, light cream in color, placed in blister packs of 21 pcs. There may be 1 or 3 blisters inside the pack. packaging with instructions.

Lindinet 20: instructions for use

Price from 381 to 2059 rubles.

The use of the hormonal drug Lindenet should be done every day at the same time to ensure their contraceptive effect. It is worth noting that Lindinet 30 is also accepted, the instructions for use are similar.

If a hormonal drug is used for the first time, then the first tablet is taken from 1 MC to 5 MC. It is necessary to take Lindinet 20 for 21 days, after which a seven-day withdrawal of the hormonal drug is provided, it is on these days that menstruation begins. Taking hormones from a new blister pack starts at 8 days. regardless of whether the withdrawal bleeding has completed or not.

Switching from another COC

The Lindinet 20 tablet will need to be taken the next day after the woman took the last COC pill from the blister. The beginning of the first menstruation proceeds as usual.

Switching from mini-pills, hormonal injectables, intrauterine systems, or implants

Hormone therapy can be started on any day of the MC if you have taken the mini-pill. When using earlier implants - on the day of removal, injection of hormones - on the day of the intended injection.

In case of switching from single drugs, it will be necessary to use barrier contraceptive measures so that the woman does not become pregnant during the first cycle of use.

After an early abortion (1st trimester)

Hormonal therapy with birth control pills should begin on the same day of surgery. Let the woman drink them according to the standard regimen; there is no need to use protection, since in this case you will not get pregnant. After an abortion, long-term hormone therapy is indicated.

After an abortion in later stages (2nd trimester)

The first Lindinet 20 tablet should be taken after 28 days. (one month) without using any additional contraceptive measures. If you take the contraceptive drug later than the specified period, for 7 days. You should additionally protect yourself from pregnancy.

If, before taking contraceptives, a woman had unprotected sexual intercourse, she should start using hormonal pills after ruling out possible pregnancy, or do something different - take the Lindinet 20 pill for the first time directly on the first day of the MC (when her own menstrual cycle begins).

Regimen for skipping pills

If you missed taking the tablets, there is no need to stop taking them; take the missed Lindinet 20 tablet as soon as you remember.

If gaps in taking pills do not exceed 12 hours, then the contraceptive effect works, barrier protection measures are not used. All subsequent tablets are taken as usual; skipping the drug does not affect the contraceptive effect.

If a woman happens to miss another dose of contraception, and the time interval exceeds 12 hours, hormonal pills are not as effective. The woman must take the pill she missed; subsequent ones are taken according to the standard regimen. Additionally, barrier methods of protection are used for 7 days. from the moment when there was a pass.

If a pill was missed and there are less than 7 pills left in the package, it is best that the woman does not take a break from taking hormonal pills. Skipping pills during the third week of contraceptive therapy does not significantly reduce its effectiveness.

It is worth considering that if you take these contraceptives continuously, you will not have periods, but breakthrough vaginal bleeding may occur while using tablets from a new blister. If after two months of continuous use of pills (including a cycle when there was a skip) menstrual-like bleeding does not occur, you should definitely rule out pregnancy while taking Lindinet 20. What to do next, consult a gynecologist, he will offer several options for solving the problem.

What to do if vomiting or diarrhea starts

If you experience vomiting or diarrhea while taking pills, and more than 3-4 hours have passed since taking the drug, this can be compared to skipping a pill, and the likelihood of pregnancy increases. What to do - take the same measures as in the case of a missed pill. If a woman does not want to change her contraceptive regimen, take Lindinet 20 tablet from a new blister.

How to postpone your period

If, with long-term use of a hormonal drug, there is a need to delay menstruation, take hormonal pills without the usual seven-day break. You can delay menstruation for any number of days, up to the end of the pills from the second blister. You should not exclude the possibility of spotting or breakthrough bleeding (this reaction of the body is considered normal). After the end of the seven-day break, you can drink Lindinet 20 as usual. What to do if you need to stop taking Lindinet, consult your gynecologist.

Use during pregnancy and pregnancy

Hormonal pills are not prescribed during pregnancy. If there is a need to use a contraceptive during lactation, you should stop breastfeeding.

Contraindications

You should not take this hormonal drug if:

Excessive sensitivity to the components of the contraceptive
Pathologies caused by impaired liver function
Pathological neoplasms in the liver
Tendency to thrombus formation, as well as thromboembolism
Serious pathologies of the cardiovascular system (including myocardial infarction)
Sickle cell anemia
Presence of estrogen-dependent neoplasms
Uterine bleeding of unknown origin
Diabetes mellitus, which occurs against the background of microangiopathy
Idiopathic jaundice
Manifestations of herpes
Pregnancy
Otosclerotic changes
Over 35 years of age (as the likelihood of developing side effects increases significantly with age).

Precautionary measures

Particular caution should be exercised in the presence of such pathological conditions and diseases:

Severe migraine-like headaches
Oncological process in the mammary glands
Frequent epileptic seizures
Pathologies of the functioning of the gallbladder (including cholelithiasis)
Increased blood pressure
Immobilization
Depressive state
Recovery period after major surgery
Diabetes
Cholestatic jaundice
Various forms of liver failure.

If the patient is over 35 years old and smokes, it is worth consulting with a specialist about the possibility of switching to Lindinet 30. It is worth noting that the woman’s age and the amount of hormones taken directly affects the contraceptive effect. After 40 years, it is worth choosing other means of contraception.

Cross-drug interactions

In accordance with the instructions for Lindient 20 and 30 inducers of liver microsomal enzymes, antibacterial drugs significantly reduce the level of estrogen in the blood, which increases the likelihood of pregnancy. Is it possible to get pregnant during this period? Yes, the probability is quite high. During the entire treatment period and over the next 7 days. upon its cessation, it is necessary to resort to the use of additional contraceptive measures.

Liver enzyme inhibitors, in turn, help increase the concentration of estrogen components in the blood.

Drugs that increase gastrointestinal motility reduce the absorption of components of hormonal pills.

Ascorbic acid slows down the process of sulfation of estrogen components and increases their bioavailability.

The hormonal agent affects the metabolic processes of cyclosporine and theophylline in the body, which can cause an unexpected reaction from various organs and systems.

You should not drink preparations with St. John's wort, as heavy menstruation (bleeding) may begin during herbal treatment.

Patients with diabetes mellitus should adjust the dosage of hypoglycemic drugs taken.

It is worth noting that the same cross-interactions occur if Lindinet 30 birth control pills are taken.

Side effects

While taking birth control pills, unwanted reactions may develop:

CVS: very rarely, thromboembolism or thrombosis may develop against the background of increased blood clotting, a sharp increase in blood pressure
Gastrointestinal tract: severe nausea and vomiting, development of hepatocellular adenoma, possible hepatitis
Reproductive system: decreased libido, heavy periods, impaired secretion of vaginal discharge
Endocrine system: weight change, feeling of tightness in the chest
Central nervous system: emotional instability, tendency to depression (during long-term hormonal therapy), frequent headaches, lethargy, increased fatigue, migraine (very severe headache).

You may also experience: pain in the lower abdomen, the occurrence of chloasma (if you are prone to it, you should avoid prolonged exposure to the sun), intolerance to contact lenses, swelling, allergies, symptoms of impaired glucose tolerance. This reaction can develop as a result of long-term use of hormones.

Overdose

If a woman has taken increased dosages of the drug, the following symptoms may be observed: nausea and vomiting, headache. An overdose may result in heavy periods.

Symptomatic therapy is recommended. What to do - consult a doctor (he will advise you to discontinue the drug) and take the prescribed medications. After this, there is a significant improvement in the general condition and cessation of bleeding. It is worth noting that there is no specific antidote.

Storage conditions and shelf life

Hormonal pills are stored at an average temperature not exceeding 30 C. The shelf life of the contraceptive is 3 years.

Analogs

Bayer Pharma, Germany

Price from 500 to 2142 rub.

Logest is similar in composition to Lindinet 20 and is a low-dose contraceptive. It is taken in the same way, it has similar contraindications, and can cause side effects similar to Lindinet. A pack contains 1 (21 tablets) or 3 (63 tablets) blister sheets. packaging.

Pros: